Lung deposition, efficacy and clinical effectiveness of spacer devices

Spacer devices in asthma.

a comparison of teachers and supervisors, with respect to teacher efficacy and reflection

supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...

The effects of static charge in spacer devices on glucocorticosteroid aerosol deposition in asthmatic patients.

Electrostatic charge in plastic spacer devices has been shown in vitro to reduce delivery of asthma medications intended for inhalation, but the effect of static charge on in vivo drug deposition is unknown. A six-way randomized crossover study was conducted in 10 mild asthmatic patients. Two plastic spacers (Nebuhaler and Volumatic) and one metal spacer (Nebuchamber) were tested. The spacers w...

[Evaluation of the influence of patient age and spacer device volume on aerosol lung deposition].

OBJECTIVE To evaluate the efficacy of three frequently used spacer devices to deliver aerosol to the lung, and to compare radioaerosol deposition with each device in different age groups. METHODS Nine healthy, non-smoking volunteers were recruited: three adults and six children, including three toddlers and three school age children. Qualitative and semi-quantitative analysis of radioaerosol ...

Pressurised aerosol deposition in the human lung with and without an "open" spacer device.

A radiotracer technique has been used to assess aerosol delivery from a pressurised metered dose inhaler, used both with and without a 10 cm cylindrical spacer attachment (Syncroner), which has an open section in its upper surface. The radionuclide technetium-99m (99mTc) was added to sodium cromoglycate in a canister (Intal inhaler; 1 mg/puff); in vitro studies with a multistage liquid impinger...